Material Safety Data Sheet for 1-Bromo-5-Chloropentane

Identification

Product Name: 1-Bromo-5-Chloropentane
Chemical Formula: C5H10BrCl
Synonyms: 5-Chloropentyl Bromide
Recommended Use: Laboratory chemical, industrial synthesis intermediate
Manufacturer: Sourced from specialty chemical suppliers
Emergency Contact Number: Refer to company-specific emergency hotline
CAS Number: 54512-75-3
UN Number: 2810
EC Number: 259-332-6
Molecular Weight: 185.49 g/mol
Address: Listed on supplier documentation

Hazard Identification

Hazard Class: Acute toxicity (oral, dermal, inhalation), Skin and eye irritation
Pictograms: Skull and crossbones, Exclamation mark
Signal Word: Danger
Hazard Statements: Harmful if swallowed, toxic in contact with skin, irritating to eyes, may cause respiratory irritation
Precautionary Statements: Avoid breathing vapors, wear protective equipment, wash exposed skin thoroughly
Chronic Exposure Risk: Repeated exposure may dry or crack skin, potential effects on liver or kidneys
Target Organs: Central nervous system, liver, kidneys
Routes of Entry: Inhalation, skin and eye contact, ingestion
Carcinogenicity: Not listed as a known carcinogen by IARC, NTP, or OSHA

Composition / Information on Ingredients

Chemical Name: 1-Bromo-5-Chloropentane
Concentration: 98-99% (typical laboratory-grade purity)
Impurities: Trace haloalkanes, moisture content below 0.5%
Other Components: None contributing to classification
CAS Registry Number: 54512-75-3

First Aid Measures

General Advice: Remove to fresh air, seek medical attention or poison control for all routes
Inhalation: Move exposed individual to fresh air, monitor breathing and pulse, give oxygen if breathing is labored
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water for at least 15 minutes
Eye Contact: Rinse eyes cautiously with water for at least 15 minutes, hold eyelids open, remove contacts if safe
Ingestion: Do not induce vomiting, rinse mouth, give water if conscious, get medical help immediately
Symptoms: Burning sensation, skin redness or swelling, coughing, dizziness, headache, possible nausea
Note to Physician: Treat symptomatically, monitor for respiratory distress or central nervous system effects

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam
Unsuitable Media: Direct water jets may disperse chemical
Fire Hazards: Vapors heavier than air, may travel and flash back, releases toxic fumes of hydrogen bromide and hydrogen chloride on combustion
Special Fire-Fighting Procedures: Wear self-contained breathing apparatus and full protective gear, prevent runoff
Explosion Hazard: Forms explosive mixtures with air above flash point
Combustion Products: Hydrogen bromide, hydrogen chloride, carbon monoxide, carbon dioxide
Flash Point: 74°C (closed cup, estimated)
Autoignition Temperature: Not well-established, handle with caution

Accidental Release Measures

Personal Precautions: Evacuate area, avoid breathing vapors, wear chemical splash goggles and resistant gloves
Environmental Precautions: Prevent spill from entering drains, waterways, or soil
Cleanup Methods: Absorb with inert material (dry sand, earth), collect in tightly closed, labeled drums for disposal
Ventilation: Use local exhaust or open windows to disperse vapors
Disposal: Contact approved hazardous waste handler, decontaminate area with appropriate cleanser
Decontamination: Wash affected surfaces with soap and water after initial cleanup
Reporting: Notify authorities in case of significant spill or public exposure

Handling and Storage

Handling: Handle in a well-ventilated environment, use proper containment to avoid spills, avoid excessive heat and open flames, do not breathe vapors, avoid contact with skin and eyes, dispense using fume hood or glove box for added safety
Storage Temperature: Store at 2-8°C in tightly sealed original container
Incompatibilities: Strong oxidizers, strong bases, reactive metals
Packaging Materials: Use containers made of glass or compatible plastics, tightly capped
Storage Location: Segregate from food, beverages, and incompatible substances, keep area labeled and restricted
Shelf Life: At least one year if stored correctly and unopened

Exposure Controls and Personal Protection

Exposure Limits: No established OSHA PEL or ACGIH TLV for 1-Bromo-5-Chloropentane, limit exposure as low as reasonably possible
Engineering Controls: Use chemical fume hood, local exhaust ventilation, and eye wash stations nearby
Personal Protective Equipment: Chemical splash goggles, impervious gloves (nitrile recommended), lab coat or chemical-resistant apron, approved respirator if vapor concentration is high
Hygiene Measures: Wash hands after handling, avoid eating or drinking during use, handle contaminated clothing carefully
Environmental Controls: Use containment trays below work stations, minimize release to air or drains

Physical and Chemical Properties

Physical State: Liquid
Color: Colorless to pale yellow
Odor: Sharp, musty, irritating
Boiling Point: 175–180°C
Melting Point: -14°C
Density: 1.375–1.395 g/cm³
Vapor Pressure: Not well-documented; estimated low volatility at room temperature
Solubility: Insoluble in water, miscible with most organic solvents
Evaporation Rate: Slow compared to diethyl ether or acetone
Viscosity: Slightly viscous
Molecular Weight: 185.49 g/mol
Partition Coefficient (log Kow): Estimated between 2 and 3
Flash Point: Approximately 74°C
Autoignition Temperature: Not precisely established
pH: Not applicable (non-aqueous)
Explosive Properties: May form explosive mixtures with air

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, may decompose with heat, light, or strong alkalies
Reactivity: Reacts with strong oxidizers, bases, and some metals
Polymerization Hazard: Not known to polymerize
Hazardous Decomposition Products: Hydrogen bromide, hydrogen chloride, possibly carbon monoxide, carbon dioxide
Conditions to Avoid: Open flames, excessive heat, strong sunlight, uncontrolled contact with bases or oxidizers
Incompatibilities: Alkali metals, potassium, sodium, chromium trioxide, nitric acid
Corrosiveness: Prolonged contact may damage certain metals and plastics

Toxicological Information

Acute Toxicity: Harmful by ingestion and skin absorption, toxic by inhalation
Potential Health Effects: Burns, headaches, dizziness, nausea, difficulties breathing, numbness of exposed skin
Skin Corrosion/Irritation: Causes irritation; can cause redness, burning, or blistering if exposure is prolonged
Eye Damage/Irritation: Irritating, tearing, pain, possible temporary vision disturbance
Inhalation: Irritating to respiratory tract, cough, weakness, can cause drowsiness and unconsciousness in high doses
Chronic Toxicity: Prolonged exposure may damage liver and kidney, not enough data for reproductive toxicity
Sensitization: No data for skin or respiratory sensitization
Carcinogenicity: Not considered carcinogenic based on available data
Mutagenicity/Teratogenicity: No reliable long-term studies

Ecological Information

Ecotoxicity: Toxic to aquatic life, may cause long-term adverse effects in aquatic environments
Persistence and Degradability: Not readily biodegradable, may persist in soil and water
Bioaccumulation Potential: Moderate, possible accumulation in marine organisms
Mobility in Soil: Low solubility in water, likely to be absorbed in sediments
Other Adverse Effects: May impact micro-organisms in waste treatment plants
Avoid Release: Do not allow material to reach environment, especially water bodies and sewers

Disposal Considerations

Disposal Methods: Incinerate with afterburner and scrubber, collect residue in hazardous chemical waste drums
Legal Compliance: Dispose in compliance with local, regional, national, and international regulations
Contaminated Packaging: Triple rinse containers, puncture and send to approved chemical landfill or incinerator
Disposal Agencies: Consult licensed hazardous waste disposal contractor
Do Not: Pour down drain, mix with nonhazardous waste, incinerate without environmental controls

Transport Information

UN Number: 2810
UN Proper Shipping Name: Toxic liquids, organic, n.o.s. (contains 1-Bromo-5-Chloropentane)
Transport Hazard Class: 6.1 (toxic substances)
Packing Group: III
Marine Pollutant: Yes
Transport Labels: Toxic
IMDG Code: 6.1/III
ICAO/IATA: Forbidden for transport by passenger aircraft, restricted on cargo aircraft
Special Precautions: Ensure package integrity, prevent container damage, check for leaks or signs of corrosion

Regulatory Information

TSCA (US): Listed
REACH (EU): Pre-registered or subject to registration
OSHA HazCom: Classified as hazardous
Canadian DSL/NDSL: Check with supplier; status may vary
SARA Title III: Not subject to Section 313 reporting
Right to Know Laws: Components appear in state lists such as CA, NJ, PA
Label Elements: Comply with local workplace safety, use GHS labeling
Chemical Inventories: Confirm with local authority for full list of relevant inventories